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Digital PCR Validates 8q Dosage as Prognostic Tool in Uveal Melanoma

BACKGROUND: Uveal melanoma (UM) development and progression is correlated with specific molecular changes. Recurrent mutations in GNAQ and GNA11 initiate UM development while tumour progression is correlated with monosomy of chromosome 3 and gain of chromosome 8q. Hence, molecular analysis of UM is...

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Detalles Bibliográficos
Autores principales:	Versluis, Mieke, de Lange, Mark J., van Pelt, Sake I., Ruivenkamp, Claudia A. L., Kroes, Wilma G. M., Cao, Jinfeng, Jager, Martine J., Luyten, Gre P. M., van der Velden, Pieter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357379/ https://www.ncbi.nlm.nih.gov/pubmed/25764247 http://dx.doi.org/10.1371/journal.pone.0116371

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