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Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity
The immune system is implicated in a wide range of disorders affecting the brain and is, therefore, an attractive target for therapy. Interleukin-1 (IL-1) is a potent regulator of the innate immune system important for host defense but is also associated with injury and disease in the brain. Here, w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357393/ https://www.ncbi.nlm.nih.gov/pubmed/25367678 http://dx.doi.org/10.1002/eji.201444748 |