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Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity

The immune system is implicated in a wide range of disorders affecting the brain and is, therefore, an attractive target for therapy. Interleukin-1 (IL-1) is a potent regulator of the innate immune system important for host defense but is also associated with injury and disease in the brain. Here, w...

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Detalles Bibliográficos
Autores principales:	Giles, James A, Greenhalgh, Andrew D, Davies, Claire L, Denes, Adam, Shaw, Tovah, Coutts, Graham, Rothwell, Nancy J, McColl, Barry W, Allan, Stuart M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Innate Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357393/ https://www.ncbi.nlm.nih.gov/pubmed/25367678 http://dx.doi.org/10.1002/eji.201444748

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