Genomic Landscapes of Pancreatic Neoplasia

Pancreatic cancer is a deadly disease with a dismal prognosis. However, recent advances in sequencing and bioinformatic technology have led to the systematic characterization of the genomes of all major tumor types in the pancreas. This characterization has revealed the unique genomic landscape of e...

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Detalles Bibliográficos
Autores principales: Wood, Laura D., Hruban, Ralph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and The Korean Society for Cytopathology 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357405/
https://www.ncbi.nlm.nih.gov/pubmed/25812653
http://dx.doi.org/10.4132/jptm.2014.12.26
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author Wood, Laura D.
Hruban, Ralph H.
author_facet Wood, Laura D.
Hruban, Ralph H.
author_sort Wood, Laura D.
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description Pancreatic cancer is a deadly disease with a dismal prognosis. However, recent advances in sequencing and bioinformatic technology have led to the systematic characterization of the genomes of all major tumor types in the pancreas. This characterization has revealed the unique genomic landscape of each tumor type. This knowledge will pave the way for improved diagnostic and therapeutic approaches to pancreatic tumors that take advantage of the genetic alterations in these neoplasms.
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spelling pubmed-43574052015-03-16 Genomic Landscapes of Pancreatic Neoplasia Wood, Laura D. Hruban, Ralph H. J Pathol Transl Med Review Pancreatic cancer is a deadly disease with a dismal prognosis. However, recent advances in sequencing and bioinformatic technology have led to the systematic characterization of the genomes of all major tumor types in the pancreas. This characterization has revealed the unique genomic landscape of each tumor type. This knowledge will pave the way for improved diagnostic and therapeutic approaches to pancreatic tumors that take advantage of the genetic alterations in these neoplasms. The Korean Society of Pathologists and The Korean Society for Cytopathology 2015-01 2015-01-15 /pmc/articles/PMC4357405/ /pubmed/25812653 http://dx.doi.org/10.4132/jptm.2014.12.26 Text en © 2015 The Korean Society of Pathologists/The Korean Society for Cytopathology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Wood, Laura D.
Hruban, Ralph H.
Genomic Landscapes of Pancreatic Neoplasia
title Genomic Landscapes of Pancreatic Neoplasia
title_full Genomic Landscapes of Pancreatic Neoplasia
title_fullStr Genomic Landscapes of Pancreatic Neoplasia
title_full_unstemmed Genomic Landscapes of Pancreatic Neoplasia
title_short Genomic Landscapes of Pancreatic Neoplasia
title_sort genomic landscapes of pancreatic neoplasia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357405/
https://www.ncbi.nlm.nih.gov/pubmed/25812653
http://dx.doi.org/10.4132/jptm.2014.12.26
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