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ATPase-Dependent Control of the Mms21 SUMO Ligase during DNA Repair

Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA replication, the Mms21-branch of the SUMO pathway counteracts recombination intermediates at damaged replication forks, thus facilitating sister chromatid disjunction. The Mms21 SUMO ligase docks to the...

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Detalles Bibliográficos
Autores principales: Bermúdez-López, Marcelino, Pociño-Merino, Irene, Sánchez, Humberto, Bueno, Andrés, Guasch, Clàudia, Almedawar, Seba, Bru-Virgili, Sergi, Garí, Eloi, Wyman, Claire, Reverter, David, Colomina, Neus, Torres-Rosell, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357442/
https://www.ncbi.nlm.nih.gov/pubmed/25764370
http://dx.doi.org/10.1371/journal.pbio.1002089