Genetic Background Effects on Disease Onset and Lifespan of the Mutant Dynactin p150(Glued) Mouse Model of Motor Neuron Disease

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily affecting motor neurons in the central nervous system. Although most cases of ALS are sporadic, about 5–10% of cases are familial (FALS) with approximately 20% of FALS caused by mutations in the Cu/Zn superoxide dismutase (...

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Detalles Bibliográficos
Autores principales: Heiman-Patterson, Terry D., Blankenhorn, Elizabeth P., Sher, Roger B., Jiang, Juliann, Welsh, Priscilla, Dixon, Meredith C., Jeffrey, Jeremy I., Wong, Philip, Cox, Gregory A., Alexander, Guillermo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357475/
https://www.ncbi.nlm.nih.gov/pubmed/25763819
http://dx.doi.org/10.1371/journal.pone.0117848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357475/
https://www.ncbi.nlm.nih.gov/pubmed/25763819
http://dx.doi.org/10.1371/journal.pone.0117848

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