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Cyclin C mediates stress-induced mitochondrial fission and apoptosis

Mitochondria are dynamic organelles that undergo constant fission and fusion cycles. In response to cellular damage, this balance is shifted dramatically toward fission. Cyclin C–Cdk8 kinase regulates transcription of diverse gene sets. Using knockout mouse embryonic fibroblasts (MEFs), we demonstra...

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Detalles Bibliográficos
Autores principales:	Wang, Kun, Yan, Ruilan, Cooper, Katrina F., Strich, Randy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357504/ https://www.ncbi.nlm.nih.gov/pubmed/25609094 http://dx.doi.org/10.1091/mbc.E14-08-1315

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