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Polysome arrest restricts miRNA turnover by preventing exosomal export of miRNA in growth-retarded mammalian cells
MicroRNAs (miRNAs) are tiny posttranscriptional regulators of gene expression in metazoan cells, where activity and abundance of miRNAs are tightly controlled. Regulated turnover of these regulatory RNAs is important to optimize cellular response to external stimuli. We report that the stability of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357507/ https://www.ncbi.nlm.nih.gov/pubmed/25609084 http://dx.doi.org/10.1091/mbc.E14-11-1521 |