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Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes

The retromer complex facilitates the sorting of integral membrane proteins from the endosome to the late Golgi. In mammalian cells, the efficient recruitment of retromer to endosomes requires the lipid phosphatidylinositol 3-phosphate (PI3P) as well as Rab5 and Rab7 GTPases. However, in yeast, the r...

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Detalles Bibliográficos
Autores principales: Bean, Bjorn D. M., Davey, Michael, Snider, Jamie, Jessulat, Matthew, Deineko, Viktor, Tinney, Matthew, Stagljar, Igor, Babu, Mohan, Conibear, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357511/
https://www.ncbi.nlm.nih.gov/pubmed/25609093
http://dx.doi.org/10.1091/mbc.E14-08-1281

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