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Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions

In the last decade, many papers highlighted that the histone variant H2AX and its phosphorylation on Ser 139 (γH2AX) cannot be simply considered a specific DNA double-strand-break (DSB) marker with a role restricted to the DNA damage response, but rather as a ‘protagonist’ in different scenarios. Th...

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Detalles Bibliográficos
Autores principales: Turinetto, Valentina, Giachino, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357700/
https://www.ncbi.nlm.nih.gov/pubmed/25712102
http://dx.doi.org/10.1093/nar/gkv061

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