H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing

DNA replication is a tightly regulated process that initiates from multiple replication origins and leads to the faithful transmission of the genetic material. For proper DNA replication, the chromatin surrounding origins needs to be remodeled. However, remarkably little is known on which epigenetic...

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Detalles Bibliográficos
Autores principales: Rondinelli, Beatrice, Schwerer, Hélène, Antonini, Elena, Gaviraghi, Marco, Lupi, Alessio, Frenquelli, Michela, Cittaro, Davide, Segalla, Simona, Lemaitre, Jean-Marc, Tonon, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357704/
https://www.ncbi.nlm.nih.gov/pubmed/25712104
http://dx.doi.org/10.1093/nar/gkv090

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