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Functional mapping of the plant small RNA methyltransferase: HEN1 physically interacts with HYL1 and DICER-LIKE 1 proteins

Methylation of 3′-terminal nucleotides of miRNA/miRNA* is part of miRNAs biogenesis in plants but is not found in animals. In Arabidopsis thaliana this reaction is carried out by a multidomain AdoMet-dependent 2′-O-methyltransferase HEN1. Using deletion and structure-guided mutational analysis, we s...

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Detalles Bibliográficos
Autores principales:	Baranauskė, Simona, Mickutė, Milda, Plotnikova, Alexandra, Finke, Andreas, Venclovas, Česlovas, Klimašauskas, Saulius, Vilkaitis, Giedrius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357707/ https://www.ncbi.nlm.nih.gov/pubmed/25680966 http://dx.doi.org/10.1093/nar/gkv102

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