The beta hairpin structure within ribosomal protein S5 mediates interplay between domains II and IV and regulates HCV IRES function

Translation initiation in Hepatitis C Virus (HCV) is mediated by Internal Ribosome Entry Site (IRES), which is independent of cap-structure and uses a limited number of canonical initiation factors. During translation initiation IRES–40S complex formation depends on high affinity interaction of IRES...

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Detalles Bibliográficos
Autores principales: Bhat, Prasanna, Shwetha, Shivaprasad, Sharma, Divya Khandige, Joseph, Agnel Praveen, Srinivasan, Narayanaswamy, Das, Saumitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357715/
https://www.ncbi.nlm.nih.gov/pubmed/25712089
http://dx.doi.org/10.1093/nar/gkv110

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