A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus

DNA is constantly damaged by endogenous and environmental influences. Deaminated adenine (hypoxanthine) tends to pair with cytosine and leads to the A:T→G:C transition mutation during DNA replication. Endonuclease V (EndoV) hydrolyzes the second phosphodiester bond 3′ from deoxyinosine in the DNA st...

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Detalles Bibliográficos
Autores principales: Shiraishi, Miyako, Ishino, Sonoko, Yamagami, Takeshi, Egashira, Yuriko, Kiyonari, Shinichi, Ishino, Yoshizumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357722/
https://www.ncbi.nlm.nih.gov/pubmed/25694513
http://dx.doi.org/10.1093/nar/gkv121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357722/
https://www.ncbi.nlm.nih.gov/pubmed/25694513
http://dx.doi.org/10.1093/nar/gkv121

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