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Dissecting the role of the ϕ29 terminal protein DNA binding residues in viral DNA replication

Phage ϕ29 DNA replication takes place by a protein-priming mechanism in which the viral DNA polymerase catalyses the covalent linkage of the initiating nucleotide to a specific serine residue of the terminal protein (TP). The N-terminal domain of the ϕ29 TP has been shown to bind to the host DNA in...

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Detalles Bibliográficos
Autores principales: Holguera, Isabel, Muñoz-Espín, Daniel, Salas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357725/
https://www.ncbi.nlm.nih.gov/pubmed/25722367
http://dx.doi.org/10.1093/nar/gkv127

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