Base-resolution methylation patterns accurately predict transcription factor bindings in vivo

Detecting in vivo transcription factor (TF) binding is important for understanding gene regulatory circuitries. ChIP-seq is a powerful technique to empirically define TF binding in vivo. However, the multitude of distinct TFs makes genome-wide profiling for them all labor-intensive and costly. Algor...

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Detalles Bibliográficos
Autores principales: Xu, Tianlei, Li, Ben, Zhao, Meng, Szulwach, Keith E., Street, R. Craig, Lin, Li, Yao, Bing, Zhang, Feiran, Jin, Peng, Wu, Hao, Qin, Zhaohui S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357735/
https://www.ncbi.nlm.nih.gov/pubmed/25722376
http://dx.doi.org/10.1093/nar/gkv151

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