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Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes

Genotypic methods for drug susceptibility testing of Mycobacterium tuberculosis are desirable to speed the diagnosis and proper therapy of tuberculosis (TB). However, the numbers of genes and polymorphisms implicated in resistance have proliferated, challenging diagnostic design. We developed a micr...

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Detalles Bibliográficos
Autores principales: Pholwat, Suporn, Liu, Jie, Stroup, Suzanne, Gratz, Jean, Banu, Sayera, Rahman, S. M. Mazidur, Ferdous, Sara Sabrina, Foongladda, Suporn, Boonlert, Duangjai, Ogarkov, Oleg, Zhdanova, Svetlana, Kibiki, Gibson, Heysell, Scott, Houpt, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357996/
https://www.ncbi.nlm.nih.gov/pubmed/25714709
http://dx.doi.org/10.1128/mBio.02273-14

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