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Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes
Genotypic methods for drug susceptibility testing of Mycobacterium tuberculosis are desirable to speed the diagnosis and proper therapy of tuberculosis (TB). However, the numbers of genes and polymorphisms implicated in resistance have proliferated, challenging diagnostic design. We developed a micr...
Autores principales: | Pholwat, Suporn, Liu, Jie, Stroup, Suzanne, Gratz, Jean, Banu, Sayera, Rahman, S. M. Mazidur, Ferdous, Sara Sabrina, Foongladda, Suporn, Boonlert, Duangjai, Ogarkov, Oleg, Zhdanova, Svetlana, Kibiki, Gibson, Heysell, Scott, Houpt, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357996/ https://www.ncbi.nlm.nih.gov/pubmed/25714709 http://dx.doi.org/10.1128/mBio.02273-14 |
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