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High-Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficile
Clostridium difficile is the most common cause of antibiotic-associated intestinal infections and a significant cause of morbidity and mortality. Infection with C. difficile requires disruption of the intestinal microbiota, most commonly by antibiotic usage. Therapeutic intervention largely relies o...
Autores principales: | Dembek, Marcin, Barquist, Lars, Boinett, Christine J., Cain, Amy K., Mayho, Matthew, Lawley, Trevor D., Fairweather, Neil F., Fagan, Robert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358009/ https://www.ncbi.nlm.nih.gov/pubmed/25714712 http://dx.doi.org/10.1128/mBio.02383-14 |
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