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Digital Gangrene an Unusual Presentation of Takayasu's Arteritis
CONTEXT: Takayasu arteritis (TA) is a chronic inflammatory disease involving large vessels like aorta and its major branches. It presents to clinician with features of arm claudication, stroke, asymmetrical pulse, or asymmetrical blood pressure in both limbs. Digital gangrene may be occurred seconda...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358052/ https://www.ncbi.nlm.nih.gov/pubmed/25789252 http://dx.doi.org/10.4103/1947-2714.152082 |
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author | Roy, Manoj Kumar Datta, Joydip Lahiri, Durjoy Agarwal, Rakesh Mukhopadhyay, Sumanto Mukhopadhyay, Jotideb Mondal, Anupam Maity, Pranab |
author_facet | Roy, Manoj Kumar Datta, Joydip Lahiri, Durjoy Agarwal, Rakesh Mukhopadhyay, Sumanto Mukhopadhyay, Jotideb Mondal, Anupam Maity, Pranab |
author_sort | Roy, Manoj Kumar |
collection | PubMed |
description | CONTEXT: Takayasu arteritis (TA) is a chronic inflammatory disease involving large vessels like aorta and its major branches. It presents to clinician with features of arm claudication, stroke, asymmetrical pulse, or asymmetrical blood pressure in both limbs. Digital gangrene may be occurred secondary to various systemic diseases like diabetes, thrombophilic states, vascular embolism, and medium and small vessel vasculitis or infections. Through evaluation to diagnose the exact etiology and timely intervention is needed to prevent progression of the gangrene which at the time can be life-threatening. Digital gangrene as an initial presentation in TA is very rare. In medical literature, there are only few case reports have been reported. CASE REPORT: We are reporting a case of a 26-year-old female patient presented with right little finger and index finger gangrene, ultimately diagnosed as TA and responded dramatically to treatment. CONCLUSION: Though rare, TA should be taken in the differential diagnosis for work up in a case of digital gangrene and it necessitates more studies in this field to uncover the exact pathophysiology for such presentation. |
format | Online Article Text |
id | pubmed-4358052 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43580522015-03-18 Digital Gangrene an Unusual Presentation of Takayasu's Arteritis Roy, Manoj Kumar Datta, Joydip Lahiri, Durjoy Agarwal, Rakesh Mukhopadhyay, Sumanto Mukhopadhyay, Jotideb Mondal, Anupam Maity, Pranab N Am J Med Sci Case Report CONTEXT: Takayasu arteritis (TA) is a chronic inflammatory disease involving large vessels like aorta and its major branches. It presents to clinician with features of arm claudication, stroke, asymmetrical pulse, or asymmetrical blood pressure in both limbs. Digital gangrene may be occurred secondary to various systemic diseases like diabetes, thrombophilic states, vascular embolism, and medium and small vessel vasculitis or infections. Through evaluation to diagnose the exact etiology and timely intervention is needed to prevent progression of the gangrene which at the time can be life-threatening. Digital gangrene as an initial presentation in TA is very rare. In medical literature, there are only few case reports have been reported. CASE REPORT: We are reporting a case of a 26-year-old female patient presented with right little finger and index finger gangrene, ultimately diagnosed as TA and responded dramatically to treatment. CONCLUSION: Though rare, TA should be taken in the differential diagnosis for work up in a case of digital gangrene and it necessitates more studies in this field to uncover the exact pathophysiology for such presentation. Medknow Publications & Media Pvt Ltd 2015-02 /pmc/articles/PMC4358052/ /pubmed/25789252 http://dx.doi.org/10.4103/1947-2714.152082 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Roy, Manoj Kumar Datta, Joydip Lahiri, Durjoy Agarwal, Rakesh Mukhopadhyay, Sumanto Mukhopadhyay, Jotideb Mondal, Anupam Maity, Pranab Digital Gangrene an Unusual Presentation of Takayasu's Arteritis |
title | Digital Gangrene an Unusual Presentation of Takayasu's Arteritis |
title_full | Digital Gangrene an Unusual Presentation of Takayasu's Arteritis |
title_fullStr | Digital Gangrene an Unusual Presentation of Takayasu's Arteritis |
title_full_unstemmed | Digital Gangrene an Unusual Presentation of Takayasu's Arteritis |
title_short | Digital Gangrene an Unusual Presentation of Takayasu's Arteritis |
title_sort | digital gangrene an unusual presentation of takayasu's arteritis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358052/ https://www.ncbi.nlm.nih.gov/pubmed/25789252 http://dx.doi.org/10.4103/1947-2714.152082 |
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