Vaccinia Virus Protein A49 Is an Unexpected Member of the B-cell Lymphoma (Bcl)-2 Protein Family

Vaccinia virus (VACV) encodes several proteins that inhibit activation of the proinflammatory transcription factor nuclear factor κB (NF-κB). VACV protein A49 prevents translocation of NF-κB to the nucleus by sequestering cellular β-TrCP, a protein required for the degradation of the inhibitor of κB...

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Detalles Bibliográficos
Autores principales: Neidel, Sarah, Maluquer de Motes, Carlos, Mansur, Daniel S., Strnadova, Pavla, Smith, Geoffrey L., Graham, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358236/
https://www.ncbi.nlm.nih.gov/pubmed/25605733
http://dx.doi.org/10.1074/jbc.M114.624650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358236/
https://www.ncbi.nlm.nih.gov/pubmed/25605733
http://dx.doi.org/10.1074/jbc.M114.624650

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