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New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors

Among the epigenetic marks, DNA methylation is one of the most studied. It is highly deregulated in numerous diseases, including cancer. Indeed, it has been shown that hypermethylation of tumor suppressor genes promoters is a common feature of cancer cells. Because DNA methylation is reversible, the...

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Detalles Bibliográficos
Autores principales:	Gros, Christina, Fleury, Laurence, Nahoum, Virginie, Faux, Céline, Valente, Sergio, Labella, Donatella, Cantagrel, Frédéric, Rilova, Elodie, Bouhlel, Mohamed Amine, David-Cordonnier, Marie-Hélène, Dufau, Isabelle, Ausseil, Frédéric, Mai, Antonello, Mourey, Lionel, Lacroix, Laurent, Arimondo, Paola B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358266/ https://www.ncbi.nlm.nih.gov/pubmed/25525263 http://dx.doi.org/10.1074/jbc.M114.594671

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