Cargando…

A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family

A large group of bacterial virulence autotransporters including AIDA-I from diffusely adhering E. coli (DAEC) and TibA from enterotoxigenic E. coli (ETEC) require hyperglycosylation for functioning. Here we demonstrate that TibC from ETEC harbors a heptosyltransferase activity on TibA and AIDA-I, de...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Qing, Lu, Qiuhe, Wan, Xiaobo, Song, Feng, Xu, Yue, Hu, Mo, Zamyatina, Alla, Liu, Xiaoyun, Huang, Niu, Zhu, Ping, Shao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358343/
https://www.ncbi.nlm.nih.gov/pubmed/25310236
http://dx.doi.org/10.7554/eLife.03714