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The DREAM complex promotes gene body H2A.Z for target repression

The DREAM (DP, Retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell cycle genes, but its mechanism of action is poorly understood. Here we show that Caenorhabditis elegans DREAM targets have an unusual pattern of high gene body HTZ-1/H2A.Z. In mutants of l...

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Detalles Bibliográficos
Autores principales: Latorre, Isabel, Chesney, Michael A., Garrigues, Jacob M., Stempor, Przemyslaw, Appert, Alex, Francesconi, Mirko, Strome, Susan, Ahringer, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358402/
https://www.ncbi.nlm.nih.gov/pubmed/25737279
http://dx.doi.org/10.1101/gad.255810.114

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