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FDA approved drugs as potential Ebola treatments
In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising in vitro activity. These compounds were not originally developed as antivirals and some have been further tested in mouse in vivo models. We put forward the opinio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358410/ https://www.ncbi.nlm.nih.gov/pubmed/25789163 http://dx.doi.org/10.12688/f1000research.6164.2 |
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author | Ekins, Sean Coffee, Megan |
author_facet | Ekins, Sean Coffee, Megan |
author_sort | Ekins, Sean |
collection | PubMed |
description | In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising in vitro activity. These compounds were not originally developed as antivirals and some have been further tested in mouse in vivo models. We put forward the opinion that some of these drugs could be evaluated further and move into the clinic as they are already FDA approved and in many cases readily available. This may be important if there is a further outbreak in future and no other therapeutic is available. |
format | Online Article Text |
id | pubmed-4358410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-43584102015-03-17 FDA approved drugs as potential Ebola treatments Ekins, Sean Coffee, Megan F1000Res Opinion Article In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising in vitro activity. These compounds were not originally developed as antivirals and some have been further tested in mouse in vivo models. We put forward the opinion that some of these drugs could be evaluated further and move into the clinic as they are already FDA approved and in many cases readily available. This may be important if there is a further outbreak in future and no other therapeutic is available. F1000Research 2015-03-10 /pmc/articles/PMC4358410/ /pubmed/25789163 http://dx.doi.org/10.12688/f1000research.6164.2 Text en Copyright: © 2015 Ekins S and Coffee M http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/publicdomain/zero/1.0/ Data associated with the article are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication). |
spellingShingle | Opinion Article Ekins, Sean Coffee, Megan FDA approved drugs as potential Ebola treatments |
title | FDA approved drugs as potential Ebola treatments |
title_full | FDA approved drugs as potential Ebola treatments |
title_fullStr | FDA approved drugs as potential Ebola treatments |
title_full_unstemmed | FDA approved drugs as potential Ebola treatments |
title_short | FDA approved drugs as potential Ebola treatments |
title_sort | fda approved drugs as potential ebola treatments |
topic | Opinion Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358410/ https://www.ncbi.nlm.nih.gov/pubmed/25789163 http://dx.doi.org/10.12688/f1000research.6164.2 |
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