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Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells

The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor mRNAs has the potential to regenerate cardiac tis...

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Detalles Bibliográficos
Autores principales:	Lee, Kunwoo, Yu, Pengzhi, Lingampalli, Nithya, Kim, Hyun Jin, Tang, Richard, Murthy, Niren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358644/ https://www.ncbi.nlm.nih.gov/pubmed/25834424 http://dx.doi.org/10.2147/IJN.S75124

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