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Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells
The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor mRNAs has the potential to regenerate cardiac tis...
Autores principales: | Lee, Kunwoo, Yu, Pengzhi, Lingampalli, Nithya, Kim, Hyun Jin, Tang, Richard, Murthy, Niren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358644/ https://www.ncbi.nlm.nih.gov/pubmed/25834424 http://dx.doi.org/10.2147/IJN.S75124 |
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