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Large conductance Ca(2+)‐activated K(+) (BK) channels promote secretagogue‐induced transition from spiking to bursting in murine anterior pituitary corticotrophs

KEY POINTS: Corticotroph cells of the anterior pituitary are electrically excitable and are an integral component of the hypothalamic‐pituitary‐adrenal axis which governs the neuroendocrine response to stress. Corticotrophs display predominantly single spike activity under basal conditions that tran...

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Detalles Bibliográficos
Autores principales: Duncan, Peter J., Şengül, Sevgi, Tabak, Joël, Ruth, Peter, Bertram, Richard, Shipston, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358680/
https://www.ncbi.nlm.nih.gov/pubmed/25615909
http://dx.doi.org/10.1113/jphysiol.2015.284471