Vimentin regulates activation of the NLRP3 inflammasome

Activation of the NLRP3 inflammasome and subsequent maturation of IL-1β have been implicated in acute lung injury (ALI), resulting in inflammation and fibrosis. We investigated the role of vimentin, a type III intermediate filament, in this process using three well-characterized murine models of ALI...

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Detalles Bibliográficos
Autores principales: dos Santos, Gimena, Rogel, Micah R., Baker, Margaret A., Troken, James R., Urich, Daniela, Morales-Nebreda, Luisa, Sennello, Joseph A., Kutuzov, Mikhail A., Sitikov, Albert, Davis, Jennifer M., Lam, Anna P., Cheresh, Paul, Kamp, David, Shumaker, Dale K., Budinger, G. R. Scott, Ridge, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358756/
https://www.ncbi.nlm.nih.gov/pubmed/25762200
http://dx.doi.org/10.1038/ncomms7574

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