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Characterization of CD8(+) T Cell Differentiation following SIVΔnef Vaccination by Transcription Factor Expression Profiling
The onset of protective immunity against pathogenic SIV challenge in SIVΔnef-vaccinated macaques is delayed for 15-20 weeks, a process that is related to qualitative changes in CD8(+) T cell responses induced by SIVΔnef. As a novel approach to characterize cell differentiation following vaccination,...
Autores principales: | Billingsley, James M., Rajakumar, Premeela A., Connole, Michelle A., Salisch, Nadine C., Adnan, Sama, Kuzmichev, Yury V., Hong, Henoch S., Reeves, R. Keith, Kang, Hyung-joo, Li, Wenjun, Li, Qingsheng, Haase, Ashley T., Johnson, R. Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358830/ https://www.ncbi.nlm.nih.gov/pubmed/25768938 http://dx.doi.org/10.1371/journal.ppat.1004740 |
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