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Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model

BACKGROUND: Mitochondrial dysfunction is a hallmark of neurodegenerative diseases including Alzheimer’s disease (AD), with morphological and functional abnormalities limiting the electron transport chain and ATP production. A contributing factor of mitochondrial abnormalities is loss of nicotinamide...

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Detalles Bibliográficos
Autores principales:	Long, Aaron N, Owens, Katrina, Schlappal, Anna E, Kristian, Tibor, Fishman, Paul S, Schuh, Rosemary A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358858/ https://www.ncbi.nlm.nih.gov/pubmed/25884176 http://dx.doi.org/10.1186/s12883-015-0272-x

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