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A Naturally Occurring Null Variant of the NMDA Type Glutamate Receptor NR3B Subunit Is a Risk Factor of Schizophrenia
Hypofunction of the N-methyl-D-aspartate type glutamate receptor (NMDAR) has been implicated in the pathogenesis of schizophrenia. Here, we investigated the significance of a common human genetic variation of the NMDAR NR3B subunit that inserts 4 bases within the coding region (insCGTT) in the patho...
Autores principales: | Matsuno, Hitomi, Ohi, Kazutaka, Hashimoto, Ryota, Yamamori, Hidenaga, Yasuda, Yuka, Fujimoto, Michiko, Yano-Umeda, Satomi, Saneyoshi, Takeo, Takeda, Masatoshi, Hayashi, Yasunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358936/ https://www.ncbi.nlm.nih.gov/pubmed/25768306 http://dx.doi.org/10.1371/journal.pone.0116319 |
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