Modulation of Cell Metabolic Pathways and Oxidative Stress Signaling Contribute to Acquired Melphalan Resistance in Multiple Myeloma Cells

Alkylating agents are widely used chemotherapeutics in the treatment of many cancers, including leukemia, lymphoma, multiple myeloma, sarcoma, lung, breast and ovarian cancer. Melphalan is the most commonly used chemotherapeutic agent against multiple myeloma. However, despite a 70–80% initial respo...

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Detalles Bibliográficos
Autores principales: Zub, Kamila Anna, de Sousa, Mirta Mittelstedt Leal, Sarno, Antonio, Sharma, Animesh, Demirovic, Aida, Rao, Shalini, Young, Clifford, Aas, Per Arne, Ericsson, Ida, Sundan, Anders, Jensen, Ole Nørregaard, Slupphaug, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358942/
https://www.ncbi.nlm.nih.gov/pubmed/25769101
http://dx.doi.org/10.1371/journal.pone.0119857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358942/
https://www.ncbi.nlm.nih.gov/pubmed/25769101
http://dx.doi.org/10.1371/journal.pone.0119857

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