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Pleiotropy among Common Genetic Loci Identified for Cardiometabolic Disorders and C-Reactive Protein
Pleiotropic genetic variants have independent effects on different phenotypes. C-reactive protein (CRP) is associated with several cardiometabolic phenotypes. Shared genetic backgrounds may partially underlie these associations. We conducted a genome-wide analysis to identify the shared genetic back...
Autores principales: | Ligthart, Symen, de Vries, Paul S., Uitterlinden, André G., Hofman, Albert, Franco, Oscar H., Chasman, Daniel I., Dehghan, Abbas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358943/ https://www.ncbi.nlm.nih.gov/pubmed/25768928 http://dx.doi.org/10.1371/journal.pone.0118859 |
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