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HP1β Is a Biomarker for Breast Cancer Prognosis and PARP Inhibitor Therapy
Members of the heterochromatin protein 1 family (HP1α, β and γ) are mostly associated with heterochromatin and play important roles in gene regulation and DNA damage response. Altered expression of individual HP1 subtype has profound impacts on cell proliferation and tumorigenesis. We analyzed the e...
Autores principales: | Lee, Young-Ho, Liu, Xiyong, Qiu, Fuming, O’Connor, Timothy R., Yen, Yun, Ann, David K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358987/ https://www.ncbi.nlm.nih.gov/pubmed/25769025 http://dx.doi.org/10.1371/journal.pone.0121207 |
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