Cargando…

Effect of Fatty Acids on Human Bone Marrow Mesenchymal Stem Cell Energy Metabolism and Survival

Successful stem cell therapy requires the optimal proliferation, engraftment, and differentiation of stem cells into the desired cell lineage of tissues. However, stem cell therapy clinical trials to date have had limited success, suggesting that a better understanding of stem cell biology is needed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fillmore, Natasha, Huqi, Alda, Jaswal, Jagdip S., Mori, Jun, Paulin, Roxane, Haromy, Alois, Onay-Besikci, Arzu, Ionescu, Lavinia, Thébaud, Bernard, Michelakis, Evangelos, Lopaschuk, Gary D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358990/ https://www.ncbi.nlm.nih.gov/pubmed/25768019 http://dx.doi.org/10.1371/journal.pone.0120257

Ejemplares similares

Exogenous Hydrogen Sulfide (H(2)S) Protects Alveolar Growth in Experimental O(2)-Induced Neonatal Lung Injury
por: Vadivel, Arul, et al.
Publicado: (2014)

Inhibition of Serine Palmitoyl Transferase I Reduces Cardiac Ceramide Levels and Increases Glycolysis Rates following Diet-Induced Insulin Resistance
por: Ussher, John R., et al.
Publicado: (2012)

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice
por: Keung, Wendy, et al.
Publicado: (2013)

Acute Regulation of Cardiac Metabolism by the Hexosamine Biosynthesis Pathway and Protein O-GlcNAcylation
por: Laczy, Boglárka, et al.
Publicado: (2011)

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
por: Ussher, John R., et al.
Publicado: (2009)

Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells
por: Dromparis, Peter, et al.
Publicado: (2014)

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
por: Ussher, John R., et al.
Publicado: (2010)

p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology
por: Saleme, Bruno, et al.
Publicado: (2020)

Pattern of systemic antibiotic use and potential drug interactions: evaluations through a point prevalence study in Ankara University Hospitals
por: AKDEMİR KALKAN, İrem, et al.
Publicado: (2021)

SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes
por: Zhang, Yongneng, et al.
Publicado: (2021)

Na(+)/H(+) Exchanger Isoform 1-Induced Osteopontin Expression Facilitates Cardiomyocyte Hypertrophy
por: Mohamed, Iman A., et al.
Publicado: (2015)

Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction
por: Fillmore, Natasha, et al.
Publicado: (2018)

The Contribution of Cardiac Fatty Acid Oxidation to Diabetic Cardiomyopathy Severity
por: Karwi, Qutuba G., et al.
Publicado: (2021)

Loss of the fructose transporter SLC2A5 inhibits cancer cell migration
por: Groenendyk, Jody, et al.
Publicado: (2022)

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology
por: Sutendra, Gopinath, et al.
Publicado: (2013)

A Phase-2 NIH-sponsored Randomized Clinical Trial of Rituximab in Scleroderma-associated Pulmonary Arterial Hypertension Did Not Reach Significance for Its Endpoints: End of Story? Not So Fast!
por: Zhang, Yongneng, et al.
Publicado: (2021)

The time has come to pull renal cancer’s sweet tooth
por: Kinnaird, Adam, et al.
Publicado: (2019)

Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation
por: Hall, Andrew R., et al.
Publicado: (2022)

Pulmonary Arterial Hypertension
por: Michelakis, Evangelos D., et al.
Publicado: (2007)

Waiting reasons affecting the handling process at liquid bulk terminals
por: Salihoglu, Eren, et al.
Publicado: (2022)

Targeting the Brain to Protect the Heart
por: Lopaschuk, Gary D.
Publicado: (2021)

Epigenetics, inflammation and metabolism in right heart failure associated with pulmonary hypertension
por: Samson, Nolwenn, et al.
Publicado: (2017)

Involvement of PFKFB3 in Pulmonary Arterial Hypertension Pathogenesis. Is It All about Glycolysis?
por: Bonnet, Sebastien, et al.
Publicado: (2019)

Mechanisms of Cardiovascular Benefits of Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: A State-of-the-Art Review
por: Lopaschuk, Gary D., et al.
Publicado: (2020)

STAT3 signaling in pulmonary arterial hypertension
por: Paulin, Roxane, et al.
Publicado: (2012)

Inhibition of lipid metabolism exerts antitumor effects on rhabdomyosarcoma
por: Miyagaki, Satoshi, et al.
Publicado: (2021)

Post-translational Acetylation Control of Cardiac Energy Metabolism
por: Ketema, Ezra B., et al.
Publicado: (2021)

Energy Metabolism on Mitochondrial Maturation and Its Effects on Cardiomyocyte Cell Fate
por: Persad, Kaya L., et al.
Publicado: (2022)

Spontaneous Regression of Huge Cardiac Rhabdomyoma in An Infant
por: Batmaz, Gülhis, et al.
Publicado: (2000)

Fatty Acid Metabolism, Bone Marrow Adipocytes, and AML
por: Tabe, Yoko, et al.
Publicado: (2020)

Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation
por: Gopal, Keshav, et al.
Publicado: (2023)

The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis
por: Bani Hassan, Ebrahim, et al.
Publicado: (2019)

Fatty Infiltration of Skeletal Muscle: Mechanisms and Comparisons with Bone Marrow Adiposity
por: Hamrick, Mark W., et al.
Publicado: (2016)

Intraosseous Lipoma of the Calvaria in the Early Stage Resembling Normal Fatty Marrow
por: Nagase, Shunsuke, et al.
Publicado: (2022)

Effect of polybrominated biphenyls on adenylate cyclase activity in rat lung alveoli.
por: Sidhu, K S, et al.
Publicado: (1978)

Leishmania donovani bodies in bone marrow
por: Ali, Natasha, et al.
Publicado: (2014)

Autosomal Interactions and Mechanisms of Pyrethroid Resistance in House Flies, Musca domestica
por: Tian, Li, et al.
Publicado: (2011)

DNA Damage and Pulmonary Hypertension
por: Ranchoux, Benoît, et al.
Publicado: (2016)

The cancer theory of pulmonary arterial hypertension
por: Boucherat, Olivier, et al.
Publicado: (2017)

Cellular Interactions in the Human Fatty Liver
por: Sovaila, Silvia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9vo7gjsjd6t8283sn1hv1nusns