MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation

Mis-regulation (e.g. overproduction) of the human Ndc80/Hec1 outer kinetochore protein has been associated with aneuploidy and tumourigenesis, but the genetic basis and underlying mechanisms of this phenomenon remain poorly understood. Recent studies have identified the ubiquitous Ndc80 internal loo...

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Detalles Bibliográficos
Autores principales: Tang, Ngang Heok, Toda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Insights & Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359004/
https://www.ncbi.nlm.nih.gov/pubmed/25557589
http://dx.doi.org/10.1002/bies.201400175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359004/
https://www.ncbi.nlm.nih.gov/pubmed/25557589
http://dx.doi.org/10.1002/bies.201400175

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