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CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells
Regulated blood production is achieved through the hierarchical organization of dormant hematopoietic stem cell (HSC) subsets that differ in self-renewal potential and division frequency, with long-term (LT)-HSCs dividing the least. The molecular mechanisms underlying this variability in HSC divisio...
Autores principales: | Laurenti, Elisa, Frelin, Catherine, Xie, Stephanie, Ferrari, Robin, Dunant, Cyrille F., Zandi, Sasan, Neumann, Andrea, Plumb, Ian, Doulatov, Sergei, Chen, Jing, April, Craig, Fan, Jian-Bing, Iscove, Norman, Dick, John E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359055/ https://www.ncbi.nlm.nih.gov/pubmed/25704240 http://dx.doi.org/10.1016/j.stem.2015.01.017 |
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