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Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase
Leishmania protozoan parasites (Trypanosomatidae family) are the causative agents of cutaneous, mucocutaneous and visceral leishmaniasis worldwide. While these diseases are associated with significant morbidity and mortality, there are few adequate treatments available. Sterol 14alpha-demethylase (C...
Autores principales: | McCall, Laura-Isobel, El Aroussi, Amale, Choi, Jun Yong, Vieira, Debora F., De Muylder, Geraldine, Johnston, Jonathan B., Chen, Steven, Kellar, Danielle, Siqueira-Neto, Jair L., Roush, William R., Podust, Larissa M., McKerrow, James H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359151/ https://www.ncbi.nlm.nih.gov/pubmed/25768284 http://dx.doi.org/10.1371/journal.pntd.0003588 |
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