Cargando…
mTOR: A Potential Therapeutic Target in Osteoarthritis?
Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the progressive loss of articular cartilage, remodeling of the subchondral bone, and synovial inflammation. Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase that controls critical cellular processes...
Autores principales: | Pal, Bandna, Endisha, Helal, Zhang, Yue, Kapoor, Mohit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359178/ https://www.ncbi.nlm.nih.gov/pubmed/25688060 http://dx.doi.org/10.1007/s40268-015-0082-z |
Ejemplares similares
-
PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage
por: Vasheghani, Faezeh, et al.
Publicado: (2015) -
mTOR Signaling and Potential Therapeutic Targeting in Meningioma
por: Pinker, Benjamin, et al.
Publicado: (2022) -
mTOR pathway – a potential therapeutic target in stroke
por: Melanis, Konstantinos, et al.
Publicado: (2023) -
mTOR: An attractive therapeutic target for osteosarcoma?
por: Ding, Liu, et al.
Publicado: (2016) -
Targeting mTOR as a Therapeutic Approach in Medulloblastoma
por: Aldaregia, Juncal, et al.
Publicado: (2018)