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Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction
Metabolic reprogramming is a key feature of tumorigenesis that is controlled by oncogenes. Enhanced utilization of glucose and glutamine are the best-established hallmarks of tumor metabolism. The oncogene c-Myc is one of the major players responsible for this metabolic alteration. However, the mole...
Autores principales: | Fogal, Valentina, Babic, Ivan, Chao, Ying, Pastorino, Sandra, Mukthavaram, Rajesh, Jiang, Pengfei, Cho, Yoon-Jae, Pingle, Sandeep C., Crawford, John R., Piccioni, David E., Kesari, Santosh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359224/ https://www.ncbi.nlm.nih.gov/pubmed/25528767 |
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