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Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers

Metabolism is an important differentiating feature of cancer cells. Lactate dehydrogenases (LDH) A/B are metabolically important proteins and are involved in the critical step of inter-conversion of lactate to pyruvate. Panepoxydone (PP), a natural NF-kB inhibitor, significantly reduces the oxygen c...

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Detalles Bibliográficos
Autores principales: Arora, Ritu, Schmitt, David, Karanam, Balasubramanyam, Tan, Ming, Yates, Clayton, Dean-Colomb, Windy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359247/
https://www.ncbi.nlm.nih.gov/pubmed/25575825