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TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer

Tumor budding in colorectal cancer is likened to an epithelial-mesenchymal transition (EMT) characterized predominantly by loss of E-cadherin and up-regulation of E-cadherin repressors like TWIST1 and TWIST2. Here we investigate a possible epigenetic link between TWIST proteins and the tumor budding...

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Detalles Bibliográficos
Autores principales:	Galván, José A., Helbling, Melina, Koelzer, Viktor H., Tschan, Mario P., Berger, Martin D., Hädrich, Marion, Schnüriger, Beat, Karamitopoulou, Eva, Dawson, Heather, Inderbitzin, Daniel, Lugli, Alessandro, Zlobec, Inti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359262/ https://www.ncbi.nlm.nih.gov/pubmed/25528769

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