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Human Antibody Production in Transgenic Animals

Fully human antibodies from transgenic animals account for an increasing number of new therapeutics. After immunization, diverse human monoclonal antibodies of high affinity can be obtained from transgenic rodents, while large animals, such as transchromosomic cattle, have produced respectable amoun...

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Detalles Bibliográficos
Autores principales: Brüggemann, Marianne, Osborn, Michael J., Ma, Biao, Hayre, Jasvinder, Avis, Suzanne, Lundstrom, Brian, Buelow, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359279/
https://www.ncbi.nlm.nih.gov/pubmed/25467949
http://dx.doi.org/10.1007/s00005-014-0322-x