Cargando…

Human Antibody Production in Transgenic Animals

Fully human antibodies from transgenic animals account for an increasing number of new therapeutics. After immunization, diverse human monoclonal antibodies of high affinity can be obtained from transgenic rodents, while large animals, such as transchromosomic cattle, have produced respectable amoun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brüggemann, Marianne, Osborn, Michael J., Ma, Biao, Hayre, Jasvinder, Avis, Suzanne, Lundstrom, Brian, Buelow, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Basel 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359279/ https://www.ncbi.nlm.nih.gov/pubmed/25467949 http://dx.doi.org/10.1007/s00005-014-0322-x

Ejemplares similares

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies
por: Harris, Katherine E., et al.
Publicado: (2018)

Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies
por: Ouisse, Laure-Hélène, et al.
Publicado: (2017)

Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies
por: Clarke, Starlynn C., et al.
Publicado: (2019)

Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies
por: Chen, Weihsu C., et al.
Publicado: (2018)

Production of pharmaceutical proteins by transgenic animals
por: Houdebine, Louis-Marie
Publicado: (2009)

Antibody manufacture in transgenic animals and comparisons with other systems
por: Houdebine, Louis-Marie
Publicado: (2002)

Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity
por: Ros, Francesca, et al.
Publicado: (2020)

Transgenic animal bioreactors
por: Houdebine, Louis Marie
Publicado: (2000)

Transgenic Production of an Anti HIV Antibody in the Barley Endosperm
por: Hensel, Goetz, et al.
Publicado: (2015)

Transgenic milk as a method for the production of recombinant antibodies
por: Pollock, Daniel P, et al.
Publicado: (1999)

Human Monoclonal Antibodies from Transgenic Mice
por: Lonberg, N.
Publicado: (2008)

Production of Recombinant Proteins in the Milk of Transgenic Animals: Current State and Prospects
por: Shepelev, M. V., et al.
Publicado: (2018)

Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview
por: Floss, Doreen Manuela, et al.
Publicado: (2007)

Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells
por: Drabek, Dubravka, et al.
Publicado: (2016)

Neuropathology of transgenic HD animal models
por: Li, Xiaojiang, et al.
Publicado: (2012)

Molecular Farming: Transgenic Animals as Bioreactors
por: Brunt, Jennifer Van
Publicado: (1988)

Ethical Issues of Transplanting Organs from Transgenic Animals into Human Beings
por: Behnam Manesh, Shima, et al.
Publicado: (2014)

Applications of Monoclonal Antibodies in Animal Health and Production
por: RAYBOULD, T.J.G.
Publicado: (1989)

Production of Recombinant Monoclonal Antibodies in the Egg White of Gene-Targeted Transgenic Chickens
por: Mukae, Takehiro, et al.
Publicado: (2020)

Human SCARB2 Transgenic Mice as an Infectious Animal Model for Enterovirus 71
por: Lin, Yi-Wen, et al.
Publicado: (2013)

An update on the tools for creating transgenic animal models of human diseases – focus on atherosclerosis
por: Volobueva, A.S., et al.
Publicado: (2019)

Genomics and Ethics: The Case of Cloned and/or Transgenic Animals
por: de Montera, Béatrice
Publicado: (2003)

Use of Transgenic Animals in Biotechnology: Prospects and Problems
por: Maksimenko, O. G., et al.
Publicado: (2013)

Transgenic Animals in Pharmaceutical and Biological Research in Iran
por: Faizi, Mehrdad
Publicado: (2013)

EXPRESSION OF RECOMBINANT PROTEINS IN THE MILK OF TRANSGENIC ANIMALS
por: Meade, H.M., et al.
Publicado: (1999)

A review of transgenic animal techniques and their applications
por: Shakweer, W. M. E., et al.
Publicado: (2023)

In Pursuit of Stability Enhancement of a Prostate Cancer Targeting Antibody Derived from a Transgenic Animal Platform
por: Venkataramani, Sathya, et al.
Publicado: (2020)

Production of recombinant human proinsulin in the milk of transgenic mice
por: Qian, Xi, et al.
Publicado: (2014)

Heavy chain–only antibodies are spontaneously produced in light chain–deficient mice
por: Zou, Xiangang, et al.
Publicado: (2007)

Recent developments in the use of transgenic plants for the production of human therapeutics and biopharmaceuticals
por: Teli, Nilesh P., et al.
Publicado: (2004)

Application of monoclonal antibodies in animal production: A review
por: Booman, P.
Publicado: (1988)

Optimization of a direct spectrophotometric method to investigate the kinetics and inhibition of sialidases
por: Hayre, Jasvinder Kaur, et al.
Publicado: (2012)

Transgenic animal models for the production of human immunocompounds in milk to prevent diarrhea, malnourishment and child mortality: perspectives for the Brazilian Semi-Arid region
por: Bertolini, Luciana, et al.
Publicado: (2014)

Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms
por: Cameron, Beatrice, et al.
Publicado: (2020)

Generating and manipulating transgenic animals using transposable elements
por: Largaespada, David A
Publicado: (2003)

Expression Systems and Species Used for Transgenic Animal Bioreactors
por: Wang, Yanli, et al.
Publicado: (2013)

Other Transgenic Animal Models Used in Cardiovascular Studies
por: Gross, David R.
Publicado: (2009)

Editorial: Animal models and transgenic technology in Craniofacial biology
por: Iwata, Junichi
Publicado: (2023)

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies
por: Gillis, Caitlin, et al.
Publicado: (2014)

Functional recombinant human anti-HAV antibody expressed in milk of transgenic mice
por: Zhang, Ran, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_nd7l9t8sus9a07m7hlecm3euro