Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIP(L) degradation, Ripoptosome formation and autophagy-mediated apoptosis

Drug resistance is a major hurdle in anticancer chemotherapy. Combined therapy using drugs with distinct mechanisms of function may increase anticancer efficacy. We have recently identified the novel chalcone derivative, chalcone-24 (Chal-24), as a potential therapeutic that kills cancer cells throu...

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Detalles Bibliográficos
Autores principales: Shi, Shaoqing, Wang, Qiong, Xu, Jennings, Jang, Jun-Ho, Padilla, Mabel T., Nyunoya, Toru, Xing, Chengguo, Zhang, Lin, Lin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359321/
https://www.ncbi.nlm.nih.gov/pubmed/25682199

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