Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis

Cofilin is a member of the actin-depolymerizing factor (ADF) family protein, which plays an essential role in regulation of the mitochondrial apoptosis. It remains unclear how cofilin regulates the mitochondrial apoptosis. Here, we report for the first time that natural compound 4-methylthiobutyl is...

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Detalles Bibliográficos
Autores principales: Li, Guobing, Zhou, Jing, Budhraja, Amit, Hu, Xiaoye, Chen, Yibiao, Cheng, Qi, Liu, Lei, Zhou, Ting, Li, Ping, Liu, Ehu, Gao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359335/
https://www.ncbi.nlm.nih.gov/pubmed/25595902

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