Human neural stem cell transplantation in ALS: initial results from a phase I trial

BACKGROUND: We report the initial results from a phase I clinical trial for ALS. We transplanted GMP-grade, fetal human neural stem cells from natural in utero death (hNSCs) into the anterior horns of the spinal cord to test for the safety of both cells and neurosurgical procedures in these patients...

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Detalles Bibliográficos
Autores principales: Mazzini, Letizia, Gelati, Maurizio, Profico, Daniela Celeste, Sgaravizzi, Giada, Projetti Pensi, Massimo, Muzi, Gianmarco, Ricciolini, Claudia, Rota Nodari, Laura, Carletti, Sandro, Giorgi, Cesare, Spera, Cristina, Domenico, Frondizi, Bersano, Enrica, Petruzzelli, Francesco, Cisari, Carlo, Maglione, Annamaria, Sarnelli, Maria Francesca, Stecco, Alessandro, Querin, Giorgia, Masiero, Stefano, Cantello, Roberto, Ferrari, Daniela, Zalfa, Cristina, Binda, Elena, Visioli, Alberto, Trombetta, Domenico, Novelli, Antonio, Torres, Barbara, Bernardini, Laura, Carriero, Alessandro, Prandi, Paolo, Servo, Serena, Cerino, Annalisa, Cima, Valentina, Gaiani, Alessandra, Nasuelli, Nicola, Massara, Maurilio, Glass, Jonathan, Sorarù, Gianni, Boulis, Nicholas M, Vescovi, Angelo L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359401/
https://www.ncbi.nlm.nih.gov/pubmed/25889343
http://dx.doi.org/10.1186/s12967-014-0371-2

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