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Dexamethasone in osteogenic medium strongly induces adipocyte differentiation of mouse bone marrow stromal cells and increases osteoblast differentiation
BACKGROUND: Osteoblasts and adipocytes share a common mesenchymal stem cell origin. Therefore, it has been suggested that the accumulation of marrow adipocytes observed in bone loss is caused by a shift in the commitment of mesenchymal stem cells from the osteogenic pathway to the adipogenic pathway...
Autores principales: | Ghali, Olfa, Broux, Odile, Falgayrac, Guillaume, Haren, Nathalie, van Leeuwen, Johannes PTM, Penel, Guillaume, Hardouin, Pierre, Chauveau, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359404/ https://www.ncbi.nlm.nih.gov/pubmed/25887471 http://dx.doi.org/10.1186/s12860-015-0056-6 |
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