Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings

Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective...

Descripción completa

Detalles Bibliográficos
Autores principales: Nasri, Hamid, Rafieian-Kopaei, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359408/
https://www.ncbi.nlm.nih.gov/pubmed/25793062
_version_ 1782361399927767040
author Nasri, Hamid
Rafieian-Kopaei, Mahmoud
author_facet Nasri, Hamid
Rafieian-Kopaei, Mahmoud
author_sort Nasri, Hamid
collection PubMed
description Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects.
format Online
Article
Text
id pubmed-4359408
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Tehran University of Medical Sciences
record_format MEDLINE/PubMed
spelling pubmed-43594082015-03-19 Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings Nasri, Hamid Rafieian-Kopaei, Mahmoud Iran J Pediatr Review Article Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects. Tehran University of Medical Sciences 2014-10 2014-09-12 /pmc/articles/PMC4359408/ /pubmed/25793062 Text en Copyright © 2014 by Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical Sciences, All rights reserved This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Nasri, Hamid
Rafieian-Kopaei, Mahmoud
Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
title Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
title_full Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
title_fullStr Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
title_full_unstemmed Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
title_short Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings
title_sort metformin and diabetic kidney disease: a mini-review on recent findings
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359408/
https://www.ncbi.nlm.nih.gov/pubmed/25793062
work_keys_str_mv AT nasrihamid metforminanddiabetickidneydiseaseaminireviewonrecentfindings
AT rafieiankopaeimahmoud metforminanddiabetickidneydiseaseaminireviewonrecentfindings

Ejemplares similares