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Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients
Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the selective degeneration of motor neurons in the brain and spinal cord progressively leading to paralysis and death. Current diagnosis of ALS is based on clinical assessment of related symptoms. The clinical manifestati...
Autores principales: | Paré, Bastien, Touzel-Deschênes, Lydia, Lamontagne, Rémy, Lamarre, Marie-Soleil, Scott, François-Dominique, Khuong, Hélène T, Dion, Patrick A, Bouchard, Jean-Pierre, Gould, Peter, Rouleau, Guy A, Dupré, Nicolas, Berthod, François, Gros-Louis, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359444/ https://www.ncbi.nlm.nih.gov/pubmed/25637145 http://dx.doi.org/10.1186/s40478-014-0181-z |
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