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Drug sensitivity in cancer cell lines is not tissue-specific
BACKGROUND: Cancer cell lines have a prominent role in the initial stages of drug discovery, facilitating high-throughput screening of potential drugs. However, their clinical relevance remains controversial. FINDINGS: We assess whether drug sensitivity in cancer cell lines is able to discriminate t...
Autores principales: | Jaeger, Samira, Duran-Frigola, Miquel, Aloy, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359490/ https://www.ncbi.nlm.nih.gov/pubmed/25881072 http://dx.doi.org/10.1186/s12943-015-0312-6 |
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